As reported in the annual securities report, 2025-12-31.
| Foreign institutions | 77.89% |
|---|---|
| Individuals | 5.15% |
| Top 10 holders | 78.96% |
| Total shareholders | 58,967 |
How to read this: each slice is a group of investors. Foreign and financial institutions are professional money; individuals are retail shareholders; other corporations are usually business partners holding strategic stakes. A large institutional slice generally means heavier analyst coverage and more trading volume.
How to read this: each line shows how one investor group's share has moved over recent years. A rising foreign or institutional line can signal growing professional interest; a falling one the opposite. Japanese companies disclose ownership once a year, so these are annual points — read the direction over several years rather than a single step.
| Investor category | Holding % | Shareholders |
|---|---|---|
| Foreign institutions | 77.89% | 1,017 |
| Financial institutions | 13.89% | 76 |
| Individuals & others | 5.15% | 57,274 |
| Securities firms | 2.57% | 46 |
| Other corporations | 0.49% | 373 |
| Foreign individuals | 0.00% | 181 |
How to read this: a high foreign or institutional share often means the stock is widely researched and more liquid; a high individual share means retail investors hold most of the company. Percentages are of voting units.
| S.No. | Shareholder | Shares | Stake % |
|---|---|---|---|
| 1 | ROCHE HOLDING LTD(常任代理人 西村あさひ法律事務所) | 1,005,670,000 | 61.10% |
| 2 | 日本マスタートラスト信託銀行株式会社(信託口) | 141,887,000 | 8.62% |
| 3 | 株式会社日本カストディ銀行(信託口) | 58,185,000 | 3.53% |
| 4 | STATE STREET BANK AND TRUSTCOMPANY 505001(常任代理人 株式会社みずほ銀行決済営業部) | 22,990,000 | 1.39% |
| 5 | THE CHASE MANHATTAN BANK, N.A. LONDON SECS LENDING OMNIBUS ACCOUNT(常任代理人 株式会社みずほ銀行決済営業部) | 21,987,000 | 1.33% |
| 6 | JP MORGAN CHASE BANK 385864(常任代理人 株式会社みずほ銀行決済営業部) | 12,191,000 | 0.74% |
| 7 | SMBC日興証券株式会社 | 11,197,000 | 0.68% |
| 8 | JP MORGAN CHASE BANK 385781(常任代理人 株式会社みずほ銀行決済営業部) | 9,479,000 | 0.57% |
| 9 | 住友生命保険相互会社(常任代理人 株式会社日本カストディ銀行) | 9,150,000 | 0.55% |
| 10 | HSBC HONG KONG-TREASURY SERVICES A/C ASIAN EQUITIES DERIVATIVES(常任代理人 香港上海銀行東京支店) | 7,499,000 | 0.45% |
Trust banks such as Master Trust and Custody Bank appear at the top of most Japanese registers: they hold shares on behalf of many underlying funds rather than owning them outright.